臨床化学
Online ISSN : 2187-4077
Print ISSN : 0370-5633
ISSN-L : 0370-5633
脳糖脂質のホルマリン固定後の組成変化
鈴木 京子横井 晋山田 芳輝新井 信隆松下 正明
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1990 年 19 巻 2 号 p. 131-135

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Changes of glycolipids in the brain after formalin fixation were examined. Quantity of lipids in the brain decreased rapidly after formalin fixation. Glycolipids decreased to 50% 24 hours after fixation, and to 10% after 4 months after fixation. Fatty acid composition of glycolipids showed a change characterized by both a diminution of long-chain fatty acids (C: 16-20) and an increase of long-chain fatty acid (C: 23-27) 4months after fixation, and its change was more markedly noted in normal fatty acids than hydroxy fatty acids.
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