臨床化学
Online ISSN : 2187-4077
Print ISSN : 0370-5633
ISSN-L : 0370-5633
A Decrease in DNA Concentration and Changes in RNA/DNA and Protein/DNA Ratios in the Cerebella of Cerebellar Mutants of Mice
M. YOKELLC. H. YOON
著者情報
ジャーナル フリー

1974 年 3 巻 1 号 p. 92-99

詳細
抄録
DNA, RNA and protein concentrations in the cerebella of cerebellar mutants, “weaver,” “weaver heterozygote,” “staggerer,” and “reeler” were examined. There was a significant decrease in the DNA concentration in the cerebella of all types of mutants. The RNA concentration was also lower in some mutant cerebella. However, the concentration of protein showed little change in most cases. The RNA/DNA ratio was lower in the mutant cerebellum at an earlier stage, but it was significantly higher at later stages in the cerebella of all types of mutants. The protein/DNA ratio, on the other hand, was always higher in the mutant cerebella. Biological significance of these findings was discussed.
著者関連情報
© Japan Society of Clinical Chemistry
前の記事 次の記事
Top