臨床化学
Online ISSN : 2187-4077
Print ISSN : 0370-5633
ISSN-L : 0370-5633
尿中17-KS 測定に於るサイフロテロンの干渉
山口 賀久林 長藏
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1978 年 7 巻 2 号 p. 192-193

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Interference of Cyproterone Acetate which is an alkyl substituted steroid used as a drug for anti-androgen was observed on urinary 17-ketosteroids assay. This drug used for patients, sometimes for child, with abnormal high androgen activity is metabolized to 17-keto derivatives and interfer on the 17-ketosteroids assay. Color by Zimmermann reaction from patients urine was orange-brown. and it is impossible to correct the value so that it is prefered to stop the administration of the drug before the test.
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