8.新規オーキシン極性輸送阻害剤の生理活性と作用機構(口頭発表)

抄録

Auxin is plant hormone that regulates diverse developmental processes including apical dominance, gravitropism, and phototropism. Auxin is polar transported to its site of action from its production. This polar auxin transport produces an asymmetric auxin distribution to respond environmental stimulus. Therefore, the auxin transport system plays a crucial role in proper plant development. Auxin is actively transported by auxin influx and efflux carriers/transporters localized in plant cell membrane. Auxin efflux carrier proteins, PIN and auxin transporters ABCB/PGP are thought to play major role in the polar auxin movement. Therefore, inhibitor of PIN and ABCB/PGP proteins would be useful chemical tools for the investigation of physiological role and molecular action of auxin transport. We here demonstrate the new polar auxin transport (PAT) inhibitors with novel mode of action. New PAT inhibitor, auxin analogues directly blocks PIN and ABCB/PGP functions and inhibits IAA movement of Arabidopsis and Maize plants.