Clinical experiences of late-onset deep venous thrombosis after kidney transplantation

Abstract

We report four cases of late onset deep venous thrombosis (DVT) after kidney transplantation. The median age was 62.5 years (range 21～69). The mean duration after transplantation was 70.5 months (range 25.9～143.5). All of patients were male. Two patients suffered acute antibody-mediated rejection, which responded to steroids. All of patients received tacrolimus, mycophenolate mofetil, methylprednisolone as immunosuppressant. All thrombolic events were symptomatic for pain or swelling of legs. Three DVTs are at same side of kidney transplantation, one patient had bilateral iliac vein thrombosis. All patients were treated with intravenous sodium heparin and then with oral warfarin. No patients developed thrombotic complications and symptoms of legs disappeared after treatment.