1983 Volume 2 Pages 5-9
Various ocular symptoms such as increased lacrymation, protrusion of the eyeball from the orbital cavity, opacification of the cornea, disclosed nictitating membrane and pupilloplegia were frequently observed in a closed-colony of the Japanese White rabbit (Oryctolagus cuniculus var. domesticus). Histopathological examination revealed the disease entity of these symptoms to be buphthalmia, ie. congenital glaucoma. Sixteen of 24 clinically healthy rabbits from the present colony including 7 sucklings also exhibited some of the glaucomatous lesions. The incidence and morphology of the lesions in Fontana's space and intrascleral channal indicated that they represent the pressure atrophy due to an increase in intraocular pressure rather than hypoplasia or aplasia of the drainage angle.
