2021 年 24 巻 p. 48-52
The chemical 2-phenoxyethanol (2-PE) is used as a preservative in pharmaceuticals and cosmetics. In this study, toxicity testing was conducted to determine the chronic toxicity of 2-PE on reproduction of Daphnia magna. Its toxicity on the growth of D. magna was also evaluated as an optional endpoint. The no observed effect concentration (NOEC) for growth and reproduction was 46.9 mg/L. Our results indicate that the concentration of 2-PE, which induces adverse effects on the growth and reproduction of D. magna, was much higher than the concentrations measured in Japanese urban rivers.