日本産科婦人科内視鏡学会雑誌
Online ISSN : 1884-5746
Print ISSN : 1884-9938
症例報告
子宮筋腫と鑑別が困難であった Low-grade endometrial stromal sarcomaの1例
山口 貴史須賀 新青井 裕美國見 聡子三輪 綾子関根 花栄河村 彩山田 敦子小泉 朱里永井 富裕子糸賀 知子西岡 暢子
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2016 年 31 巻 2 号 p. 393-398

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  Low-grade Endometrial stromal sarcoma is a rare tumor that constitutes less than 1% of malignant uterine tumors. Because low-grade endometrial stromal sarcoma is located in the myometrium, it can be easily confused with uterine leiomyoma or adenomyosis uteri, so its diagnosis is often based on the postoperative pathology report. We present a case where low-grade ESS was diagnosed after a total laparoscopic hysterectomy (TLH) performed in the presence of an undiagnosed endometrial stromal sarcoma. A 48-year- old woman (who had had 4 pregnancies, 4 births) with a chief complaint of hypermenorrhea was referred to our department. Pelvic ultrasound and MRI revealed a degenerative interstitial leiomyoma that measured 23×20mm. We performed TLH. Histopathologic examination revealed a cellular neoplasm composed of spindle cells with myometrial invasion and lymphatic invasion. The tumor cells were positive for CD10 and for smooth-muscle actin, which resulted in the diagnosis of low-grade endometrial stromal sarcoma. After obtaining the patient's consent we performed bilateral salpingo-oophorectomy 3 months after the TLH. Lack of gross dissemination and negative peritoneal cytology were confirmed at the second surgery. The follow-up at 3 months after the second surgery TLH has been favorable.
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