腹腔鏡で二期的手術を行った若年型顆粒膜細胞腫の1例

抄録

  We performed a two-stage laparoscopic surgery in granulosa cell tumor of juvenile type. It was controversial that borderline tumors of the ovary were safely treated by laparoscopy.

  A 12-year-old woman was referred to our hospital for irregular menses. Magnetic resonance imaging (MRI) of the pelvis revealed a 6cm-sized solid and cystic mass, and uterine endometrium was thick. Serum estradiol was high level, and LDH and AFP were within normal limits. The laparoscopic procedure was done. The tumor was soft, and we could strip the tumor from right ovary easily. Microscopically, tumor cells which were composed hyperchromatic nuclei, eosinophilic or clear cytoplasm showed in a diffuse sheet-like pattern or in loose short fascicles or a trabecular growth fashion. Mitotic figures were encountered in some areas. The feature was compatible with granulosa cell tumor of juvenile type. A two-stage laparoscopic surgery performed was right salpingo-oophorectomy.