JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY
Online ISSN : 1884-5746
Print ISSN : 1884-9938
Case report
A case of pelvic lymph node positive for FDG-PET/CT after endometrial cancer surgery and diagnosed as mycobacterial lymphadenitis after laparoscopic biopsy
Tadahisa TakeuchiHiroyasu NakajimaAyano TsubomiAi AnamiAi TanakaYuichi Nakazono
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2025 Volume 41 Issue 2 Pages 72-76

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Abstract

Patient: A 36-year-old woman with a BMI of 34 who had no significant past medical or family history. Six months after undergoing laparoscopic simple total hysterectomy, bilateral salpingo-oophorectomy, and pelvic lymphadenectomy for stage IA endometrial cancer, contrast-enhanced CT scan revealed a pelvic lymph node enlarged to 15 mm in short diameter. FDG-PET/CT scan was performed to differentiate recurrence, revealing FDG accumulation in the same area, which raised suspicion for metastasis. Laparoscopic exploration and biopsy were performed for diagnostic and therapeutic purposes. During the surgery, no significant abnormalities were noted in the abdominal or pelvic cavity aside from postoperative changes. An enlarged lymph node was identified and excised from the area caudal to the left deep iliac circumflex vein. Pathological examination of the excised specimen revealed no malignant findings; however, numerous small granulomas were observed in the enlarged lymph node. Ziehl Neelsen staining showed a few positive acid-fast bacilli, leading to a diagnosis of mycobacterial lymphadenitis. Since all other tests for mycobacteria were negative, no additional treatment was administered, and a policy of careful observation was adopted.

Conclusion: This case illustrates a solitary mycobacterial lymphadenitis, which had not been previously reported as a condition requiring differentiation from malignant diseases in FDG-PET/CT scans. Laparoscopic biopsy proved useful as a method for differentiation in lymph nodes where malignancy could not be ruled out by FDG-PET/CT, as it provides better visualization and magnification.

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© 2025 Japan Society of Gynecologic and Obstetric Endoscopy and Minimally Invasive Therapy
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