抄録
We examined the effect of glycyrrhizin (GL) on the production of platelet-activating factor (PAF) from mouse hepatic sinusoidal endothelial cells. GL was shown to significantly suppress the production of PAF from the mouse sinusoidal endothelial cells stimulated with calcium ionophore A 23187.
This result suggests that GL may act on sinusoidal endothelial cells and have an influence on the local hepatic inflammatory reactions by the suppression of PAF production.
