抄録
The molecules involved in the cell adhesion have been extensively studied in recent years, and our understanding of adhesion has advanced in molecular basis. Although it seems to be clear that the adhesion between leukocytes and endothelial cells or extracellular matrix proteins has a key role in the inflammatory reaction, much attention has little been paid so far, particularly in the clinical field.
In this review, recent progress and details of the functional and structural aspects of the adhesion molecules were summarized. Understanding of the molecular mechanism of inflammation by focusing on the cell-cell and cell-matrix interaction may contribute to clarify the pathogenesis of the disease, and to develop a new strategy against the disease.
