Abstract
The effects of Margarita extract on superoxide generation of human PMN were investigatedin vitroby using chemiluminescence method with a 2-methyl-6-phenyl-3, 7-dihydroimidazo [1, 2-a] pyrazin-3-one (CLA) . Superoxide generation stimulated by N-formyl-methionyl-leucyl-phenylalanine (FMLP) or phorbol myristate acetate (PMA) was suppressed with Margarita extract dose dependently with statistic significance at a rate of 67, 41, 34% with FMLP and 42, 33% with PMA in respective dose of 0.5, 1.0, 1.5 mg/2 ml and of 1.0, 1.5 mg/2 ml.
The results suggest that Margarita extract has an anti-oxidative action through suppressing superoxide generation.
