1996 年 16 巻 6 号 p. 425-436
We investigated the effect of far infrared ray (4-14 μm-or growth ray-) emitting stones or products on several inflammatory parameters of human leukocytes, leukemia cell lines, neoplasma and RA patients. [Ca2+] i, chemotaxis, phagocytosis and O-2 generation by neutrophils, blastogenesis to PHA by lymphocytes were significantly increased 60 min after the test tubes containing neutrophils and lymphocytes were surrounded with these stones and products. [Ca2+] i was slightly increased in HL60, unchanged in ML1 and decreased in K562, respectively. The growth of Sarcoma 180 cells or B-16 melanoma transplanted from tumor mice was inhibited by covering the back of the mice with clothes which were produced from the powder of the crushed stones or ceramics. Lipid peroxidation was also decreased by surrounding the bottom of test tubes with test materials. Among the four test materials, SGES showed the marked effect on the above parameters, especially on lipid peroxidation. HgC12-induced hepatitis in rat was well improved by the administration of micropowder of the crushed SGES. Eighty five RA patients at exacerbated stages were also administered micro-powder of SGES and subjected for taking bath which is produced from SGES. In about half of the patients, their clinical symptoms and/or the levels of CRP and ESR were improved. Their serum lipid peroxide levels were decreased. Since iatrogenic disorders have recently been social problem, not chemically synthetic, but natural far infrared ray emitting stones or products without any side effect may be recommended for medical treatment.