抄録
It has been elucidated that phagocyte-released oxygen intermediates which are excessively generated to fuse invading agents in their phagosomes induce auto-oxidative damage such as tissue injury in several human cells in vivo. Dr. Yukie Niwa has found that AOA (anti-oxidants analogs) are potent scavengers of oxygen intermediates from many natural plants after the treatment that are heating with ultra red ray and brewing with Koji.
We tried to treat with AOA on the collagen disease patients. A patient with PSS was significant improvement in both their clinical symptoms and laboratory findings.
We think that AOA may be useful drug in collagen disease.