抄録
To determine if rheumatoid arthritis patients on gold sodium thiomalate (GST) can be maintained on auranofin (AF), we examined a group 111 patients, who had been stable on GST.
The patients were randomized to receive either AF 6 mg daily, or continued GST. Patients eligible for study showed no difference in clinical outcome after 6 months of treatment.
On-therapy conditions in the 2 groups were similar, with the exception of diarrhoea in 29.8% of the AF-treated group.
And there were no correlation between blood gold concentration and safety & efficiency.
This study shows that AF may be substituted for GST during rheumatoid arthritis therapy.
