抄録
We analysed kinetics of phagocytosis by using the whole blood and fluorescent microspheres with flow cytometry. The rate of phagocytosis (y) was determined by the T/C (target particles-to-cell) ratio (x) (y=K1×log (x) +K2 K1, K2: constant) . We defined the Phagocytosis 50 (Ph 50) that indicated the value of T/C ratio in which 50% of phagocytes injested the particles. The Ph 50 might be the new general parameter of phagocytosis independent of several conditions.
The Ph 50 in cases of systemic lupus erythematosus (SLE) were statistically higher than in normal controls, which indicated the decreased phagocytic activity in SLE.
