抄録
The purpose of our current study was to evaluate differences between periosteal graft and Perichondrial graft performed using the same experimental method for full-thickness articular cartilage defects in the rabbit model. Thirty adult Japanese white rabbits were used. Full-thickness cartilage defects were created in the articular surface of the patellar groove down to the subchondral bone. Periosteal grafts were harvested from the anteromedial surface of the proximal tibia, and perichondrial grafts were harvested from the cartilagous part of the lower rib. The autograft was fixed directly by human fibrin glue (TisseelTM), with the cambium layer facing the joint space. The repair was evaluated histologically using a scoring system at five days, and at one, two, four, six, 10 and 12 weeks after grafting. At one week after operation, the mesenchymal cell proliferated under the fibrous layer of the periosteal and perichondrial graft. At two weeks, the defect was filled with immature appearing chondrocytes. At four weeks, mature chondrocytes were observed throughout the defect, and matrix was stained dy safranin-O.Our current study showed that these were no significant differences between the periosteal graft and perichondrial graft.
