悪性リンパ腫を合併した慢性関節リウマチの一例
1986 年 5 巻 3 号 p. 437-443
詳細
1986 年 5 巻 3 号 p. 437-443
An increased incidence of malignant lymphoma has been suggested to occur in various auto-immune diseases. Rheumatoid arthritis (RA) is the commonest of these diseases, but the risk of malignancy in RA is very rare. However we encountered a case of RA which showed an intimate relationship with malignant lymphoma.
This case was a man who had suffered from RA since 15 years old. He had continuously been given various kinds of drugs including steroids and gold, but not within the previous 10 years. At age of 40, a tumor was discovered on the left elbow and he received two excisions for it. The diagnosis of malignant lymphoma was confirmed after the second excision. The laboratory examinations showed a positive CRP-test, negative RA-test, normal immunoglobulins-IgA 271mg/dl, IgG 1255 and IgM 116 - and so on. He was given anti-cancer chemotherapy (ADM and 5-Fu) and irradiation (Co-60) after the excision. At the present time, he is 46 years old and there has been no evidence of recurrence or metastasis.
