2000 年 13 巻 1 号 p. 72-79
The reason that “ the best implant system” in dental practice has not been determined is due to kind of raw material, shape and structure of the implants, and various procedures in surgical operation.
As the JIAD KOM implant system has been popularized gradually in the clinical field, the histopathological reaction between host and implanted piece was investisated. According to KOM system, 9 implant pieces composed of grade 2 titanium were embedded into mandibular bone of 3 dogs, 3 pieces in each. The dogs were sacrificed under anesthesia at 6,8, and 12 weeks after surgical operation. The host bones with implanted pieces, which were fixed with 4% paraformaldehyde before sampling, embedded in paraffin, sectioned and stained with H.E. and Movat's stain, and made SEM preparations according to routine procedures, were examined using a light microscope and EPMA (Electron Probe X-ray Microanalizer).
All implants were appreciable in every term after implantation. Microscopically, stabile sustained osseointegration was shown in the surface of host bones in all implants in every term. At 6 weeks after implantation, immature bony matrix was formed on the surface bordering the implant piece. Bony tissue hardened at 8 weeks. The osseointegration and ossification were stable 12 weeks after implantation. The mucosa and submucosa of gingiva wounded by a drill showed a normal healing process of second intention with flattened epithelial papillae and fibrosis with newly-formed blood vessels in the submucosa. No inflammatory reaction was suggested by abscess formation or round cell accumulation. The EPMA findings coincided with those of histomorphologic observations. Dissolution and dispersion of raw materials (Titanium) in the newly-formed bone tissue were not detected.