Epidemiological analysis of multicentric and unicentric Castleman disease and TAFRO syndrome in Japan

Yasufumi Masaki; Hiroshi Kawabata; Shino Fujimoto; Mitsuhiro Kawano; Noriko Iwaki; Takeharu Kotani; Akikatsu Nakashima; Nozomu Kurose; Kazue Takai; Ritsuro Suzuki; Sadao Aoki

doi:10.3960/jslrt.19021

この記事には本公開記事があります。本公開記事を参照してください。
引用する場合も本公開記事を引用してください。

Epidemiological analysis of multicentric and unicentric Castleman disease and TAFRO syndrome in Japan

Yasufumi Masaki , Hiroshi Kawabata, Shino Fujimoto, Mitsuhiro Kawano, Noriko Iwaki, Takeharu Kotani, Akikatsu Nakashima, Nozomu Kurose, Kazue Takai, Ritsuro Suzuki, Sadao Aoki

著者情報

キーワード: disease incidence, Statistical Research Committee of Japanese Society of Hematology, specific use survey, fixed-point observation method

ジャーナルフリー早期公開

論文ID: 19021

DOI https://doi.org/10.3960/jslrt.19021

この記事には本公開記事があります。

The final version of this article is now available: Vol. 59 (2019), No. 4 pp. 175-178

詳細

抄録

Castleman disease is a polyclonal lymphoproliferative disease which is clinically classified into unicentric (UCD) and multicentric (MCD). TAFRO syndrome is a relatively new concept that partly overlaps with MCD. Due to their rarity, their incidence remains unknown. This study investigated the incidence and prevalence of UCD, MCD, and TAFRO syndrome in Japan using a fixed-point observation method based on their incidence in Ishikawa prefecture. The annual incidences of MCD, UCD, and TAFRO syndrome in Japan were 309-731, 71-542, and 110-502, respectively, yielding annual incidence rates per million individuals of 2.4-5.8, 0.6-4.3, and 0.9-4.9, respectively, and nationwide prevalence of 4,180-14,900, 1,350-10,300, and 860-7,240, respectively. In conclusion, MCD, UCD and TAFRO syndrome may not be as rare as previously estimated in Japan.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）