2016 Volume 37 Issue 1 Pages 98-105
Recently, low-reactive level laser therapy (LLLT) has been used to the infertile patients in area of reproductive medicine. This therapy is proposed to be effective and impressive results to improve the pregnancy rate. However, the mechanism of the improvement of ovarian function by LLLT has been unclear in detail. Our results showed that VEGF is induced by LLLT through mechanisms involving MAPK in human granulosa cells. LLLT would promote various ovulatory phenomena as well as follicular growth.