A Terahertz Microfluidic Chip for Ultra-trace Biosensing

Abstract

Biosensing with terahertz (THz) waves is receiving a lot of attentions due to the potential for extracting the important information on the vital function without any fluorescent labels. However, due to the diffraction limit of THz waves and the strong absorption into water, it is challenging to develop compact chip sensors that capable of quantitative and high-sensitive measurement of ultra-trace amount of solution. To overcome these difficulties, here, we present a nonlinear optical crystal-based THz microfluidic chip with a few arrays of split ring resonators and investigate possibility of ultra-trace biosensing with THz waves.