Spectral Diffuse Reflectance Imaging Based on Numerical Simulation for Light Transport in Biological Tissues

Abstract

Diffuse optical spectroscopy provides functional and morphological information of living tissues based on optical absorption and scattering properties. Diffuse reflectance spectroscopy (DRS) can be achieved with simple and low cost equipment, and has been widely applied to in vivo measurements and imaging of biological tissues. In the present article, in vivo evaluation of hemodynamics and changes in tissue morphology by using DRS based on the Monte Carlo simulation for light transport in biological tissues and its application to biomedical imaging are described.