Abstract

To investigate the effect of laserthermia in CIN, we performed fundamental study and clinical trial, using Nd-YAG laser. As the result of fundamental study using OMC-i which was established from a uterine cervical squamous cell carcinoma, the antitumor effect of laserthermia was confirmed. We devised aluminium reflector, in which Intralipid dilution injected, as a novel method of laserthermia in the uterine cervix.
Laserthermia was performed in 15 patients included 8 cases of mild dysplasia, 6 cases of severe dysplasia and 1 case of intraepithelial cancer. Seven cases (46.7%) showed disease free after three months of laserthermia. Therefore, although irradiation method needs to be improved further, laserthermia is considered that it should become a useful therapeutic method in the future for the CIN.