Nd-YAG Laser PDTにおける胃癌培養細胞増殖に関する検討。

門脇 徹; 中澤 慶彦; 森田 雅範; 西岡 隆見; 高橋 佳伸; 宮田 彰; 北島 裕慎; 松本 浩利; 山崎 一明; 西森 功; 佐野 修一; 壽美 貴守; 鍵山 惣一; 坂本 芳也; 中田 博文; 岡崎 和一; 山本 泰朗; 山本 泰猛

doi:10.2530/jslsm1980.11.Supplement_155

Evaluation of photodynamic effects of pheophorbide-a and Nd-YAG Laser irradiation on proliferation of human gastric cancer cells

T. Kadowaki, Y. Nakazawa, M. Morita, T. Nishioka, Y. Takahashi, A. Miyata, H. Kitazima, H. Matsumoto, K. Yamasaki, I. Nishimori, S. Sano, T. Sumi, S. Kagiyama, Y. Sakamoto, H. Nakata, K. Okazaki, Y. Yamamoto, Y. Yamamoto

Author information

T. Kadowaki
The First Department of Internal Medicine, Kochi Medical School
Y. Nakazawa
The First Department of Internal Medicine, Kochi Medical School
M. Morita
The First Department of Internal Medicine, Kochi Medical School
T. Nishioka
The First Department of Internal Medicine, Kochi Medical School
Y. Takahashi
The First Department of Internal Medicine, Kochi Medical School
A. Miyata
The First Department of Internal Medicine, Kochi Medical School
H. Kitazima
The First Department of Internal Medicine, Kochi Medical School
H. Matsumoto
The First Department of Internal Medicine, Kochi Medical School
K. Yamasaki
The First Department of Internal Medicine, Kochi Medical School
I. Nishimori
The First Department of Internal Medicine, Kochi Medical School
S. Sano
The First Department of Internal Medicine, Kochi Medical School
T. Sumi
The First Department of Internal Medicine, Kochi Medical School
S. Kagiyama
The First Department of Internal Medicine, Kochi Medical School
Y. Sakamoto
The First Department of Internal Medicine, Kochi Medical School
H. Nakata
The First Department of Internal Medicine, Kochi Medical School
K. Okazaki
The First Department of Internal Medicine, Kochi Medical School
Y. Yamamoto
The First Department of Internal Medicine, Kochi Medical School
Y. Yamamoto
The First Department of Internal Medicine, Kochi Medical School

JOURNAL FREE ACCESS

1990 Volume 11 Issue Supplement Pages 155-158

DOI https://doi.org/10.2530/jslsm1980.11.Supplement_155

Details

Abstract

We evaluated the effect of photodynamic therapy (PDT) with pheophorbide-a (PpA) as a photosensitizing agent and pulsed Nd-YAG Laser (1064nm) on human gastric cancer cells (Hs 746T) by MTT (methyl-thiazolylte-trazolium ) assay.
Optical density (O. D.) of MTT assay decreased slightly immediately after irradiation, but remarkably decreased successively 1 and 3 days after irradiation in the group treated with PpA more than 34.6 μg/ml, which represented that the number of living cells decreased,

Corresponding author

Register with J-STAGE for free!