日本レーザー医学会誌
Online ISSN : 1881-1639
Print ISSN : 0288-6200
ISSN-L : 0288-6200
マウス培養知覚神経節に対する低出力レーザーの影響
陳 明裕藤田 邦夫石井 準之助島田 桂吉平田 たつみ藤澤 肇
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1991 年 12 巻 Supplement 号 p. 269-272

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We applied low power laser irradiation on cultured dorsal root ganglion (DRG) which was excised from mouse, Continuous wave Ga-Al-As diode laser of 830nm wave length and 20mW power output was irradiated for 5-15 minutes. Neurite elongation from DRG was inhibited significantly by laser irradiation. It also inhibited neurite elongation of single neuron isolated from DRG. Especially that of small diameter neuron was significantly inhibited.
By immunostaining, neurites including substance P and/or CGRP were shown to he affected severely. These results suggest that inhibitory effect of laser irradiation on neurite elongation may relate to the mechanism of pain attenuation.
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© 特定非営利活動法人 日本レーザー医学会
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