Abstract
Photodynamic therapy (PDT) by means of the photosensitzer PHE and the excimer dye laser (EDL) was first approved by the Japanese government for early stage lung cancer (stage 0 and stage I), esophagus cancer, stomach cancer, cervical cancer and its dysplasia. The construction of the approved excimer dye laser, optical probes for laser exposure and a colposcope for PDT application are described in this paper. We had good treatment results for stage 0 lung cancer, esophagus cancer, stomach cancer, cervical cancer and its dysplasia in the clinical investigational trial of PDT, but not good for stage I lung cancer and bladder cancer because of the imperfection of laser exposure. The reason of the effect of PDT to the deep site of tumor by usig EDL was discussed.