日本レーザー医学会誌
Online ISSN : 1881-1639
Print ISSN : 0288-6200
ISSN-L : 0288-6200
子宮頚部上皮内腫瘍に対するレーザー蒸散療法
-凍結療法との比較検討-
齋藤 俊章坂井 邦裕小林 裕明重松 敏之上平 謙二光本 正宗加来 恒壽嘉村 敏治
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1995 年 16 巻 Supplement 号 p. 197-200

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Between 1985 and 1994, two hundred and nineteen patients with biopsy proven cervical intraepithelial neoplasia (CIN) with satisfactory colposcopy were treated with the carbon dioxide laser, and 178 patients were treated with cryosurgery in an outpatient setting. There was no statistical differences in the incidence of persistent disease, cumulative cure rate calculated by Kaplan-Meier Method between the two treatment groups. However, there was a tendency that Laser treatment had lower persistent rate and higer cure rate in the CIN grade 3. Laser vaporization had statistically higer incidence of treatment related hemorrhage. On the other hand, troublesome watery discharge was prominent in the cryosurgery patients. Invasive squamous cell carcinoma has not been identified in either treatment group in the follow up period. These results reconfirm the efficacy and safety of laser vaporization for all form of CIN.
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