Abstract
It has been previously reported that the near-UV Excitation AutofluorescenceSystem has been developed to detect oral cancers using differences in tissue autofluorescence between normal and cancer. We have been observed that the tissue autofluorescence spectra of primary oral squamous cell carcinoma (SCC) had two major bands centeredat 630nm and 680nm with excitation of 410nm when this system was applied with 9 patients of primary oral SCC. Only 9 patients were evaluatedin the previous study.Therefore, more numbers of the oral cancer patients were evaluated with this system in this study. The successful detection rate of the diagnosis overall is 83%. Moreover, no matter the histological typing of tumors was SCC, adenoid cystic carcinoma or verrucous carcinoma, or no matter the lesion was the primary or the recurrent, this system was found to be useful for the clinical diagnosis. Therefore, our system could be applied to the more variety of the oral malignant tumors.
