Abstract
The dye laser with a wavelength of 585nm pulsed at 450μsec selectively reacts with red boold cells, resulting in impairment of ectatic blood vessels in dermis. It, thus, diminishes numbers and luminal diameters of abnormal blood vessels in hemangioma with minimum side effects, such as scarformation. In theory, the light of dye laser penetrates into 1,400μm depth of the human skin. However, histological examination in clinical trials have revealed that blood vessels in deep dermis reopened and circulate blood after treatments, while those at less than 600μm depth from the skin surface were completely destroyed. Clinically, substantial decrease of lesions has been achieved by the first treatments with this laser in most cases of port-wine stains, possiblly follwed by some additional improvements in the next 3 to 4 treatments, with only little efficacy thereafter. For strawberry mark, complete disapperance or satisfactory improvement of the thin flat lesions has been achieved, but the tumor type lesions remained as atrophic and redundant skin lesions or even unaffected, indicating importance of the treatments in an early stage this tumor.
