Studies on Laser Surgery

Report 10 : Effects of Nd-YAG Laser to DMBA Induced Lingual Carcinoma

Abstract

A 1%DMBA-acetone solution was applied to the tongue of male hamsters, 6-8 weeks old, and the lingual carcinoma were produced on an average in 15 weeks. These tumors were cut at its basal part with Nd-YAG laser (laser), and the carcinoma were reduced. As the control, the carcinomas were similary reduced with scissors. And then the hamsters were observed in local and general condition until they died. Ther was a case which lived for a long period by complete disappearance of carcinoma in the group with laser. But most of the carcinomas recurred within one month, and hamsters died. For the survival, evident differences were not noted between the group with laser and control.