Abstract
The effect of He-Ne laser (low-power) radiation on the wound healing of guinea pigs skin were studied in connection with three items; such as (1) collagenic hydroxyproline contents, and (2) DNA contents in the tissues, and (3) histological findings, by comparing the group treated by laser every day with untreated group.
The following results were obtained. (1) The contents of hydroxyproline in treated group after three days of incised wound was significantly lower than that of control (untreated) group. (2) The maximal contents of DNA in the treated group was recorded at the third day, and untreated group showed a peak at the fourth day. (3) From the histological findings, increase of fibroblastic cell number were observed on treated group at the third day, but there was no difference of density of collagen between both groups.
These results suggest that the low-power laser radiation accelerated composition of type III collagen for incised wound healing.
