Abstract
Since 1980, we have been studying the effect of light on experimental and clinical wound healing. Particulary its effect according to the difference of light has been studied. In October 1982, the first case underwent the light irradiation therapy. A man had a chronic ulcer of the left 1st toe due to Buerger's disease for 5 months. On the 14th day after 6 treatmemt of irradiation his ulcer completely healed. During this treatment, the patient noticed that the pain completely disappeared after 2 treatments. We believed light irradiation stimulated tissues injured and leaded some good clinical results.
Some investigations concerning mechanism for these effects; i. e. perifereal circulation, cell proliferation, histology of the granulation, chemistry and so on. From these investigations, periferal circulation was improved when the patients suffered from vascular disorders. Furthermore, irradiated G0G1 cells increase their electrophoretic mobility but irradiated G2M cells decrease their mobility. Some results suggest light irradiation comtributes homeostasis of living cells, tissues, and bodies.And some investigation concerning the light soucees, i. e. wave length, energy density and polarization. As a result, linear poralization and right circular poralization improved wound healing, but incoherent light itself does not improve wound healing. We are strongly suggested the role of coherency is very important to do light irradiation on the living body.
