Abstract
In the present paper, the authors state their experiences in the treatment of 11 cases of surgical tuberculosis which were treated with isonicatinic acid hydrazid (INAH) for more than 5 weeks selected from 25 cases which were under the treatment with INAH.
The selected cases consisted of 8 cases of tuberculosis of cervical lymphnodes, 1 case of fistulated tuberculous pyothorax, 1 case of fistulated tuberculous peritonitis and 1 case of tuberculosis of digital bone.
Only 5 of the above cases had never been treated prior to INAH treatment, and the rest of them had been treated either streptomycin, PAS or X-Ray irradiation.
During the 1 st week of the treatment, the dosage per os was 2 mg/kg, the 2 nd week 3 mg/kg, and 4 mg/kg thereafter.
As the results up until today, 6 out of 8 cases of tuberculosis of cervical lymphnodes were either cured or improved. As to the 2 cases of tuberculous fistula, which had been treated with streptomycin without success, 1 was cured in the 5 th week and another demonstrated remarkable improvement (almost complete closure of the fistula) .
Relative to the case of tuberculosis of digital bone, remarkable improvements such as diminution of swelling and favorable X-Ray findings were observed.
During the treatment, almost no side effects were noticed. In the majority of the cases, favorable changes were noted in their general conditions. Of course we know the necessity of the longer period observation, but, we can say the very favourable effect of INAHH in the treatment of surgical tuberculosis at least in the observation of this period.
