Abstract
The authors confirmed the presence of its antigenicity in vivo by immunizing humans of A Group and B Group with the carbohydrate fraction extracted from human ABS saliva according to the method by Witebsky et al.
Three subcutaneous injections of 1 mg/cc saline solution each were given at approximately 3 days' intervals. As the results of the immunization, rise of a and β agglutinin titres were recognized in 9 out of 10 A Group humans and 4 out of 5 B Group humans respectively (2 to 16, 4 in most case) . However, in 1 of each of A and B Groups, entirely no rise of agglutinin was observed. Further, in 1 case of A Group, production of the Group-specific anti-B precipitin was recognized.