Abstract
In order to investigate the influence of dulcin and its split product, p-aminophenol, on the animal in the embryonal stage, which presents entirely different conditions, the author performed experiments on the toxicity and the influence of dulcin and p-aminophenol on the development of the embryo as the first step. He further conducted histological examinations on various organs to compare the results with those published in the past papers. Next, the author traced the fate of dulcin in the developing hens egg and in the body of chick embryo, thereby he compared the results with that of saccharin in the living body to throw light, though faint, to the reason of different toxicity of both sweetening substances. The author also investigated the behavior of the hepatic enzymes, especially the proteolytic enzymes, and scrutinized the toxicity of dulcin fermentologically.
