抄録
In an attempt to observe, from the view point of the functions of reticuroendothelial system, the influence of the environment of the daily life and the conducts of life execrised on the disease resisting functions, the author investigated the fuluctuation in the carbon particle phagocytosis of neutrophile leucocytes before and after the routine works by the general industrial labourers as well as the experimental muscular exertions of approximately 7.5 in terms of R.M.R. for 30 minutes.
The followings are the outline of the results thus obtained.
1. when observed during a week, the degree as well as the rate of phagocytosis reached the maximum in the middle of a week, and showed a gradualy diminishing trend toward the end of a week. In the daily observation, they showed a gradual rise from 8 a.m. and reached the maximum at 4 p.m., demonstrating a gradually diminishing trend until 8 p.m.
2. In the case of a light work not exceeding 20 in terms of R.M.R., no change in the phagocytosis was recognized if the work-amount was less than 400, while a remarkable diminution was demonstrated when the amount of work exceeded 500. Therefore, the disease resisting function observed from the above phase was considered to have been suppressed.
3. In the case of a precision work, which is liable to induce a distinct lowering in the level of cerebral excitement, the disease resisting function seemed to be much more distinctly affected compared with the case of muscular work when observed from the view point of phagocytosis of leucocytes even if the intensity and the amount of work was small.
4. In the case when the intensity of work was approximately 7.5 in terms of R.M.R., the phagocytosis of leucocytes was found affected even when the workamount was less than 400.
5. As to the comparison of the phagocytosis of leucocytes in the corpulent and slender subjects, it seemed that corpulent subjects, who are burdened with more exertion, are more seriously affected than slender subjects are affected even if they are undertook an equall degree of work.
