Abstract
Blue and white globulin substances were isolated from 10 folds reclistilled water diluted dog plasma with acetic acid precipitation at pH 5.9.
The effects of globulin substances on rabbits were hematologically investigated.
The results were as follow.
After intravenous injection of blue globulin substances to rabbits, red cells in peripheral blood became microcytic and it's osmotic-fragility weakened.
Increase in serum caeruloplasmin value was observed with an advanced anemia following intra-venous injection of blue globuline substances which showed a marked fibrinolytic activity, moreover, oxidase activity of caeruloplasmin as diamine oxidase was investigated.
