昭和医学会雑誌
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
Monoamine Oxidaseに関する研究
第3報p-Methyphenyl Hydrazineの末梢血管に及ぼす影響
新居 昭小沢 俶男若松 英信滝内 武藤巻 達男上条 一也
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1961 年 21 巻 3 号 p. 265-269

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The influences of p-methylphenyl hydrazine (MPH), 1-isonicotinyl-2-isopropyl hydrazine (IIH) and isonicotinic acid hydrazine (INH) on the adrenaline- and tyramine-action to the rabbit ear vessel were studied.
1) The effects of tyramine on the rabbit ear blood vessel after pretreatment of MPH or IIH which are potent inhibitors of monoamine oxidase, were potentiated, but after pretreatment of INH which is a potent inhibitor of diamine oxidase, were not altered.
2) The effects of adrenaline on the rabbit ear blood vessel after pretreatment of MPH, IIH or INH were not potentiated.
3) The administration of MPH, IIH or INH to the rabbit ear blood vessel caused dilation.
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