産科領域における血清銅と血清Ceruloplasminに関する研究

第1報妊婦における血清銅と血清Ceruloplasminの消長, ならひに血色素量, 赤血球数, 白血球数の変動について

抄録

Serum Copper and Serum Ceruloplasmin at the condition of healthy nonpregnancy, normal pregnancy, vomiting of pregnancy, and toxemia of pregnancy was surveied about 113 females, reserched the alteration of Hemoglobin Value, Erythrocytes and Leucocytes count besides.
The average of the contorol group (healthy, nonpregnant females) showed: Serum Copper 97.4±14.1 γ/dl. Serum Ceruloplasmin 12.6±1.8 mg/dl, Hemoglobin Value 81.6±4.1 % Sahli, , Erythrocytes Count (417.2±11.6) ×10⁴, Leucocytes Count 6380±410.
By the occasion of normal pregnancy, Serum Copper began to increase from two-months. At the three-months it began to increase precipitously. After the four-months it increased month by month, and had an apparent increase after the nine-months again. At the ten-months pregnancy it had the highest figure.
Serum Ceruloplasimin began to increase precipitously at the three-months. After the four-months, it increased month by month and at the ten-months pregnancy, it had the highest figure.
Hemoglobin Value and Erthrocytes Count began to decrease from three-months pregnancy gradually, and show the lowest at eight-months pregnancy. But they appeared to have the rising figure after that.
Leucocytes Count appeared to have the increasing figure from the three-months pregnancy, but after that, there was no real change. At the end of Pregnancy, it began to increase again.
In Hyperemesis gravidarum, Serum Copper and Serum Ceruloplasmin increased a little more than the mean value of healthy nonpregnancy, but were apparently lower than two-months or three-months healthy pregnancy.
To compare with the mean value of healthy nonpregnancy, Hemoglobin Value and Erythrocytes count decreased in Hyperemesis gravidarum, but Leucocytes is inclined to increase in it.
In Toxemia of pregnancy, Serum Copper and Serum Ceruloplasmin was higher than the normal pregnancy's, and they apparently appeared to increase more than the end of normal pregnancy.
Hemoglobin Value in Toxemia of pregnancy showed clearly the lower than the normal pregnancy's and its Erythrocytes Count was same. But its Leucocytes Count was inclined to increase apparently.