実験的筋萎縮に関する生化学的研究

抄録

Sixteen rats were used for this study. In thirteen animals atrophy of the skeletal muscles of the left hind leg were induced by the procedure of neurotomy in the sciatic nerve of the same side.
Acetoacetic acid levels in the atrophied side were compared with the unatrophid side.
Coleman's results in the dystrophied mouse revealed the markedly elevated levels of acetoacetic acid. The same results were obtained in our atrophied cases, but the degree of the elevation of acetoacetic acid was not so marked as seen in Coleman's dystophied cases.
These results might be assumed the biochemical difference between neutrotic atrophy and myopathic atrophy.