Abstract
For the purpose of studying the significance of glucose-6-phosphate dehydrogenase in erythrocytes (E-G-6-PD) in childhood, the auther has determined E-G-6-PD obtained from healthy and sick children.
Results were as follows ;
1) E-G-6-PD activity in healthy children indicated high value in their neonatal period decreasing gradually till they reached to six months after birth and showed constant value thereafter.
2) Much higher activity of E-G-6-PD were observed in premature neonates as compared with those of matured.
3) E-G-6-PD activity in neonatal hyperbilirubinemia due to ABO incompatibility between mother and baby showed somewhat low in premature compared with matured.
4) E-G-6-PD activity of hemolytic anemia showed remarkable increase, while lower in aplastic anemia.
5) Relations between E-G-6-PD and E-GOT varied with various hematologic disorders and no significant correlation was observed.
6) Among the patients with anoxic status, both E-G-6-PD and E-GOT in congenital heart disease showed high activity, while elevated E-GOT but no elevation of E-G-6-PD wass shown in patients with asthmatic crisis.
7) E-G-6-PD activity in acute glomerulonephritis and nephrotic children remainedt within normal range regardless the presence of anemia. E-G-6-PD of diabetic child showed low value immediately after starting treatment.
