Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
Volume 33, Issue 2
Displaying 1-12 of 12 articles from this issue
  • [in Japanese]
    1973 Volume 33 Issue 2 Pages 185-191
    Published: April 28, 1973
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • Yoshiaki Mori
    1973 Volume 33 Issue 2 Pages 192-224
    Published: April 28, 1973
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Arthroscopy was employed on 531 cases, that is, 70 cases of rheumatiod arthritis, 17 cases of tuberculous arthritis, 5 cases of tumor, 11 cases of septic arthritis, 10 cases of syphilitic arthritis, and other 18 cases among arthritis, and 232 cases of the lesion of meniscus, 22 cases of the lesion of synovial wrinkles, 17 cases of joint mice, 31 cases of the fractures and the injury of ligaments and 17 cases other among the internal derangement of the knee points.
    According as cases, the progress was followed up and the following results were obtained.
    1) The resistance of the joint capsule at the puncture was depended on the age and the scar and contructure caused by inflammation.
    2) The change of the synovial villus consisted of hyperemia, proliferation, hypergenesis, degeneration, atrophy and necrosis. The degeneration and necrosis were found on typical rheumatoid arthritis, the proliferation and the hypergenesis on typical osteoarthritis and the pigmentation on typical pigmented villondular synovitis.
    3) The articular cartilage in the juvenility was pink-white, but it turned yellowish, turbid, sof tend and destroyed in the advanced age.
    4) The arthroscopy was the best method for diagnosis of meniscal disorder. The torn meniscus appeared that its fiber was irregular, and at late its surface was slived and covered with synovialis etc. The postoperated and regenerated meniscus was found too.
    5) The snapping phenomenon hardly reappeared in the knee in which the injecting sterile normal saline was inserted for arthroscopy. However, the conjuctive surface of the joint cartilage and meniscus was dynamically observed by the arthroscope and etiology could be cleared.
    6) The lesion of the synovial wrinkle that could not be diagnosed by x-ray could be found by arthroscopy.
    The progress of the knee joint disease could be almost physiologically observed and the therpeutic indications could be definitely decided, when the arthroscopy was performed with paying attention to the above metioned points.
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  • Sukehide Ito
    1973 Volume 33 Issue 2 Pages 225-233
    Published: April 28, 1973
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    JaTH 160 strain of Japanese encephalitis virus was inoculated intraperitoneally into pregnant hamsters. Vertical transmission of viral infection was followed in some animals which inoculated during the first 4 th to 10 th day of pregnancy.
    Three to 4 days after infection, immunofluorescent studies showed specific viral antigen in cytoplasm of endothelial cells located in maternal uterine blood vessels. One or two days later, specific antigen appeared in maternal placental tissue. Five to six days after infection, specific fluorescent cells increased in number forming confluent focal lesions. These lesions acted as primary foci in fetus, and the virus infection spread quite rapidly through fetal blood vessels. The infected fetus showed specific antigen in endothelial cells of capillary, cartilage membrane, heart muscles, trunc muscles, dental germs, Auerbach's plexus in gastrointestinal tract, central nervous system, lungs and kidneys.
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  • Shigehiko Kawai
    1973 Volume 33 Issue 2 Pages 235-247
    Published: April 28, 1973
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    For the purpose of studying the significance of glucose-6-phosphate dehydrogenase in erythrocytes (E-G-6-PD) in childhood, the auther has determined E-G-6-PD obtained from healthy and sick children.
    Results were as follows ;
    1) E-G-6-PD activity in healthy children indicated high value in their neonatal period decreasing gradually till they reached to six months after birth and showed constant value thereafter.
    2) Much higher activity of E-G-6-PD were observed in premature neonates as compared with those of matured.
    3) E-G-6-PD activity in neonatal hyperbilirubinemia due to ABO incompatibility between mother and baby showed somewhat low in premature compared with matured.
    4) E-G-6-PD activity of hemolytic anemia showed remarkable increase, while lower in aplastic anemia.
    5) Relations between E-G-6-PD and E-GOT varied with various hematologic disorders and no significant correlation was observed.
    6) Among the patients with anoxic status, both E-G-6-PD and E-GOT in congenital heart disease showed high activity, while elevated E-GOT but no elevation of E-G-6-PD wass shown in patients with asthmatic crisis.
    7) E-G-6-PD activity in acute glomerulonephritis and nephrotic children remainedt within normal range regardless the presence of anemia. E-G-6-PD of diabetic child showed low value immediately after starting treatment.
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  • Kenzo Sugisaki
    1973 Volume 33 Issue 2 Pages 248-262
    Published: April 28, 1973
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Human hemoglobin has been separated to adult hemoglobin (Hb-A) and fetal hemoglobin (Hb-F) by Betcke's staining method and alkali method, modified by Singer.
    In this paper Hb-F, obtained from 460 cases, including normal pregnant women, labor, puerperal women, abnormal pregnant women with various tocological diseases and fetuses, was studied according to the methods, described above.
    In addition of this, both hemoglobin and erythrocytes, obtained from umbilical vessels of pregnant women, were also investigated, in order to observe if they correlate with grade of fetal growth.
    As the results, the following relations were provided ;
    1) The amount of the Hb-F related in inverse correlation with fetal weight, heigh and maturation period
    2) Both hemoglobin and count of erythrocytes related in direct correlation with fetal weight, heigh and maturation period.
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  • Kosuke Tsuda
    1973 Volume 33 Issue 2 Pages 263-282
    Published: April 28, 1973
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Ceruloplasmin, a copper protein in the human serum, was purified with DEAE-cellulose column chromatography and alcohol-chloroform.
    The purified ceruloplasmin was labelled with radioactive iodine according to the method of Hunter. With the preliminary experiments the purified ceruloplasmin was pure in electrophoretic analysis. And it was also confirmed that 125I-labelled ceruloplasmin did not degenerate with radiation of labelled iodine itself and iodine of 125I-labelled ceruloplasmin did not move to the other protein moiety in the serum in vitro and vivo. Labelled ceruloplasmin was injected intravenously to the patients of liver disease and controls.
    Blood samples were drawn at 5 and 30, 60 min and 3, 6 and 12 hours after the injection and thereafter, daily untill the fourteenth day.
    Analysing the serum radioactivity disappearance curve, the biological half life of the injected ceruloplasmin was much longer in patients of livercirrhosis.
    The radioactivity found in urine, bile and feces, was seemed to be excreted as a component of a small molecular substances.
    It was assumed that the rate of uptake and degradation of the ceruloplasmin in the body also contributed as one of factors of controlling serum ceruloplasmin level other than those of synthetic ability in the liver.
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  • Emiko Akutsu, Santa Ichikawa
    1973 Volume 33 Issue 2 Pages 283-288
    Published: April 28, 1973
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    The effect of new antiulcerogenic drug, N-Acetyl-L-glutamine aluminium complex (KW 110), on the motility of intestine of rabbit was studied.
    KW 110 showed almost no effect on the intestinal motility even applied directly to the intestinal surface or per os during seven days. KW 110 also showed almost no antispasmodic action against the contracture produced by acetylcholine or barium chloride.
    Effects of KW 110 on the spontaneous contraction of intestine in were shown in Fig. 2. and the antispasmodic action for the barium and acetylcholine contractures Fig. 3 and 4.
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  • Toshiya Sugawara
    1973 Volume 33 Issue 2 Pages 289-305
    Published: April 28, 1973
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    A series of 115 patients with infertility was investigated to elucidate the relationship between sex and thyroid functions.
    The examinations included BMR, 131I-uptake, RSU and serum total cholesterol.
    Of 400 patients with infertility, 5.3% had hyperthyroidism and 6.5% hypothyroidism.
    Anovulation was of high incidence among cases of reduced BMR ; luteinic insufficiency among those of augmented BMR ; and abnormal menstrual cycle among those of increased 131I-uptake or reduced RSU.
    There was a tendency to obesity in patients with hypothyroidism of ovarian hypofunction.
    Administration of thyroid resulted in gestation in 28.6%, improved thyroid function in 81.2-84.2% and elevated BBT in 85.7-35.7% of patients.
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  • Hirotoshi Yamaguchi
    1973 Volume 33 Issue 2 Pages 306-319
    Published: April 28, 1973
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    A study was made on 328 cases of normal or abnormal pregnancy, pregnancy with one or several complications, non-pregnant normal women or obstetric surgery in order to investigate the intravital mechanism of serum electrolyte metabolism in pregnant women.
    Determinations were made of serum Na, K and Cl.
    Normal pregnant women had lower serum Na ank K levels than non-pregnant women (Na 140.2±2.4 mEq/l, K 3.97±0.22 mEq/l) . Serum Cl level was somewhat higher in the former than the latter group.
    Na and K levels remained unaltered, while Cl level was slightly reduced, during stages I and II of delivery. Serum K and Cl were decreased to some extent during stage III of delivery and on the 1 st puerperal day, but increased from the 3 rd puerperal day on, up to the same levels as in non-pregnant women on the 7 th puerperal day.
    Severe vomiting of pregnancy was attended by a decrease in serum electrolytes. Serum Cl, in particular, was markedly reduced down to 100±3.1 mEq/l.
    Toxemia of pregnancy was associated with a decrease in Na and an increase in K and Cl. There was a decrease in K and Cl in cases of termination-passed pregnancy (K 3.60±0.24 mEq/l, Cl 102.8±1.9 mEq/l) .
    K was decreased in inertia uteri (3.45±0.25 mEq/l)
    Serum electrolytes were decreased until 1-3 days following laparotomy and then re-turned to the preoperative levels by the 7 th-13 th postoperative day. No difference in Na or Cl level existed between umbilical and maternal blood, but umbilical blood showed a higher K level than maternal blood.
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  • Yoshishige Takahashi, Yuichi Okuyama, Michio Kimura, Fumio Sugata
    1973 Volume 33 Issue 2 Pages 320-325
    Published: April 28, 1973
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    A 27-years old woman, with chief complaints of stomack ache and port wine uria, was admitted to our hospital on Jan. 18 th, 1971. Some tests were performed with her urine. The results were as following. Schwartz-Watson test (++++) . Fischer-Brügch test (++++) . PBG 31.1 mg/l. ALA 23.8 mg/l. Coproporphyrin 359.9μg/l. Uroporphyrin 166.6μg/l.
    From these results and her symptomes, she was diagnosed as hepatic porphyria.
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  • Keizo Takahashi, Itsuro Hayakawa, Teruaki Tomaru, Isao Kagami, Mikita ...
    1973 Volume 33 Issue 2 Pages 326-328
    Published: April 28, 1973
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    The postoperative brachial plexus paralysis was observed in a young man 21 years old following the urethral plastic surgery under general anesthesia.
    He recovered almost in 5 months.
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  • Takashi Metoki, Takuo Miyata, Ikuo Meguro, Kimio Honda, Hiroshi Yogi, ...
    1973 Volume 33 Issue 2 Pages 329-337
    Published: April 28, 1973
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Two cases of hyperthermia of unknown etiology developed with general anesthesia were reported. The first case was a 27-year-old male and the second case was a 5-year-old boy. Both cases of anesthesia were induced by intravenous administration of thiamylal sodium and succinylcholine chloride and maintained with nitrous oxide-oxygen-halothane. Hyperthermia was noted after 3 hrs and 4 hrs respectively after begining of operation. Body surface cooling was performed utilizing ice bag, alchol packs and cooling blanket. Furthemore in the first case, metabolic and respiratory acidosis was corrected by administration of sodium bicarbonate and passive hyperventilation. Both cases were cured and postoperative course were uneventful. The second case was anesthetized successfully with nitrous oxide-oxygen and diallyl-nor-toxiferine during reoperation without any accident.
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