1985 Volume 45 Issue 1 Pages 19-22
11 cases of relatively unocommon benign disease, which showed lymph node swelling and skin tumor were investigated by ANAE-staining to estimate the changes of T-cells and plasma cell series in the lesion's imprints. A case of mal-absorption syndrome had a high percentage of T-cell in mesenteric lymph node, but it suggested the relative increasing sign according to B cell depletion. A case of eosinophilic granuloma was shown a slight T-cell increasing in cervical lymph node. 2 cases of Castleman-s lymphoma, hemangioma cavernosum, foreign body granuloma, state after lymphangiography, PVP deposit and pseudolymphoma were obtained no significant findings. Systemic diseases, amyloidosis and mast cell reticulosis, were revealed slight decreasing tendency of both T-cell and plasma cell series. There are several reports that the transition from eosinophilic granuloma, foreign body granuloma and amyloidosis to malignant lymphoma is occurred. We must be kept in mind, under certain circumstance, especially at local long-standing immune reaction foci, that it may happen malignant change of lymphocyte population. For prevention it, early diagnosis should be done by using not only routine histological examination but cytochemical study and immunological analysis.
