ANAE-ACTIVITIES FOR DIFFERENTIAL DIAGNOSIS AMONG HODGKIN'S DISEASE OF MIXED CELLULARITY, LYMPHOPLASMACYTOID LYMPHOMA OF PLEOMORPHIC TYPE AND IMMUNOBLASTIC LYMPHADENOPATHY

Abstract

Three diseases which show complicated histological pictures, Hodgkin's disease of mixed cellularity (19 cases), lymphoplasmacytoid lymphoma of pleomorphic type (5 cases) and immunoblastic lymphadenopathy (11 cases), were investigated by ANAE-staining to estimate T-cell and plasma cell series, moreover, to find out some changes for differential diagnosis. Two quantitative differences were obtained. 1) T-cell rest population of immunoblastic lymphadenopathy was relatively fewer than those of two other diseases. 2) Plasma cell series of Hodgkin's disease was shown considerably decrease comparing with the other two. As mentioned above, though two difference were detected, those percentages were dispersed wide distribution from case to case. We could not observe an absolute diagnostic indicator. Combined methods may be needed such complicated histological diseases to differentiate each other.