Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
THE DIFFERENCE OF T-CELL POPULATION BETWEEN INFANT AND THE AGED IN NONSPECIFIC LYMPHADENITIES
—INVESTIGATION BY ALPHA-NAPHTHYL-ACETATE-ESTERASE STAIN—
Yoshihiko SUGIYAMAHidekazu OTAAkira SHIOKAWAMiki KUSHIMAHiroshi KAJIYAMAMasabumi TAKIMOTOHideyoshi WATANABEYoshiki IIDA
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1985 Volume 45 Issue 2 Pages 201-204

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Abstract
Many reports have indicated that T cell dysfunction, i.e. decrease of response for various mitogens and allogeneic lymphocyte, weakness of rejection against transplants, disturbance of delayed hypersensitivity and loss of resistance to infection and tumor proliferation are followed by ageing. We reported here the difference of T cell number between infants and the aged in the cases of nonspecific lymphadenitis by ANAE stain. In the lymph node imprints it was shown that the aged cases were seen remarkable decrease of ANAE-Droplet positive cell (Mean value of 16 cases of the infant; 52.81%, the value of 9 cases of the aged; 26.00%, respectively) . On the contrary, plasma cell series was shown no particular difference between the two groups. It might be suggested that selective diminution of T cell reaction of the aged cases against viral infection and/or unknown antigens.
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