NONSPECIFIC LYMPHADENITIS SHOWN DIMINUTION OF T-CELL PATTERN LYMPHOCYTES BY ALPHA-NAPHTHYL-ACETETE-ESTERASE (ANAE) STAIN

Abstract

We reported here 15 cases of nonspecific lymphadenitis shown diminution ANAE-Droplet positive lymphocyte in lymph node imprints. Many reports have shown decrease of ANAE-activities of lymphocytes in the process of neoplastic disease, blastoid change of various mitogens, activated state by infection and rejected reaction of transplantation. Histological findings in most of our investigated cases were shown to become smaller T zone following remarkable follicular hyperplasia. On the other hand, as the reason of decrease of ANAE-Droplet positive cell in the cases of histologically preserved T zone might be considered to change from lymphocytes to blastoid cell and/or increase of suppressor T cell against viral infection or the other antigens.