Abstract
A 28-year-old male visited our hospital because a 4 year pain in left heel. Swelling and tarsal tunnel syndrome were found. Due to suspicion of a malignant tumor based on the clinical examination findings, operation was carried out. The tumor appeared from the aponeurosis plantaris and consisted compressed the nerve plantaris lateralis. Amputation below the knee was performed due to the malignant results of the immediate pathological diagnosis. The pathological diagnosis of the tumor was clear cell sarcoma (CCS) . CCS is characterized by a long clinical course and high mortarity. The therapeutic treatment has not been established but it is possible to decrease the size of the tumor by “CYVADACT”therapy pre-operatively. We report a case in whom the pre-operative chemothrapy was effective, and literature review of pertinent chemothrapy.