We have studied about titanium(Ti) micro porous scaffold for applying inflow and outflow's necking parts of VAD. To promote early new ingrowth of vascular intima, we developed an additional surface modification process for making the hydrophilic treatment.
Bulk Ti specimens were incubated into hydrogen peroxide solution for 48h in adequate temperature. After soaking the collagen solution on specimens' surface, top surface were fixed by the isocyanate-benzene solution.
Specimens were studied for the hydrophilic evaluation by measuring the contact angle, the quantification of collagen matrix, and the cell adhesion studies. Specimens showed fine hydrophilic properties, much fixation of collagen compared to the bulk control, and positive cell adhesion level than the control group. These results indicated the possibility of this treatment for the blood contacting devices as the promotive scaffold.
